Small molecules which reverse Crohn's disease
Canned Analysis
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General Information
AccessionDCA00009613
TitleSmall molecules which reverse Crohn's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Crohn's disease gene expression signature in the Peripheral blood mononuclear cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ca21e467bea600fb89c6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:794
Cell TypePeripheral blood mononuclear cells
DO IDDOID:8778
Disease NameCrohn's disease
Organismhuman
UMLS CUIC0156146
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM76115, GSM76116, GSM76117, GSM76118, GSM76119, GSM76120, GSM76121, GSM76122, GSM76123, GSM76124, GSM76125, GSM76126, GSM76127, GSM76128, GSM76129, GSM76130, GSM76131, GSM76132, GSM76133, GSM76134, GSM76135, GSM76136, GSM76137, GSM76138, GSM76139, GSM76
Perturbed SamplesGSM76056, GSM76057, GSM76058, GSM76059, GSM76060, GSM76061, GSM76062, GSM76063, GSM76064, GSM76065, GSM76066, GSM76067, GSM76068, GSM76069, GSM76070, GSM76071, GSM76072, GSM76073, GSM76074, GSM76075, GSM76076, GSM76077, GSM76078, GSM76079, GSM76080, GSM76
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3365
Gene Expression Omnibus
Ulcerative colitis and Crohn's disease comparison: peripheral blood mononuclear cells
19
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