Small molecules which mimic chronic lymphocytic leukemia
Canned Analysis
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General Information
AccessionDCA00009624
TitleSmall molecules which mimic chronic lymphocytic leukemia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the chronic lymphocytic leukemia gene expression signature in the Peripheral blood mononuclear cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c6e6e467bea600fb8826
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:194
Cell TypePeripheral blood mononuclear cell
DO IDDOID:1040
Disease Namechronic lymphocytic leukemia
Organismhuman
UMLS CUIC0023458
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM219478, GSM219479, GSM219480, GSM219481, GSM219482, GSM219483, GSM219484, GSM219485, GSM219486, GSM219487, GSM219488, GSM219489, GSM219510, GSM219511, GSM219512, GSM219513, GSM219514, GSM219515, GSM219516, GSM219517, GSM219518, GSM219519, GSM219520, GS
Perturbed SamplesGSM219456, GSM219457, GSM219458, GSM219459, GSM219460, GSM219461, GSM219462, GSM219463, GSM219464, GSM219465, GSM219466, GSM219467, GSM219468, GSM219469, GSM219470, GSM219471, GSM219472, GSM219473, GSM219474, GSM219475, GSM219476, GSM219477, GSM219490, GS
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8835
Gene Expression Omnibus
Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells.
7
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