Small molecules which reverse Osteoarthritis
Canned Analysis
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General Information
AccessionDCA00009635
TitleSmall molecules which reverse Osteoarthritis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Osteoarthritis gene expression signature in the Chondrocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c709e467bea600fb8838
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:199
Cell TypeChondrocyte
Disease NameOsteoarthritis
Organismhuman
UMLS CUIC0029408
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM413840, GSM413841, GSM413842, GSM413846, GSM413847, GSM413848
Perturbed SamplesGSM413843, GSM413844, GSM413845, GSM413849, GSM413850, GSM413851
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16464
Gene Expression Omnibus
Osteoarthritic chondrocytes: monolayer and matrix cultures
21
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