Small molecules which reverse osteoarthritis
Canned Analysis
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General Information
AccessionDCA00009637
TitleSmall molecules which reverse osteoarthritis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the osteoarthritis gene expression signature in the Hyaff-11 scaffold culture cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bfd8e467bea600fb84bc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:751
Cell TypeHyaff-11 scaffold culture
DO IDDOID:8398
Disease Nameosteoarthritis
Organismhuman
UMLS CUIC0157946
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM413846, GSM413847, GSM413848
Perturbed SamplesGSM413849, GSM413850, GSM413851
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16464
Gene Expression Omnibus
Osteoarthritic chondrocytes: monolayer and matrix cultures
21
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