Small molecules which reverse severe combined immunodeficiency
Canned Analysis
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General Information
AccessionDCA00009647
TitleSmall molecules which reverse severe combined immunodeficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the severe combined immunodeficiency gene expression signature in the Lung Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ba9ce467bea600fb8220
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:201
Cell TypeLung Tissue
DO IDDOID:627
Disease Namesevere combined immunodeficiency
Organismmouse
UMLS CUIC0085110
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM76963, GSM76964, GSM76965
Perturbed SamplesGSM76966, GSM76967, GSM76968
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3414
Gene Expression Omnibus
Lung immune response to Nippostrongylus brasiliensis infection: time course
7
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