Small molecules which mimic ankylosing spondylitis
Canned Analysis
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General Information
AccessionDCA00009648
TitleSmall molecules which mimic ankylosing spondylitis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the ankylosing spondylitis gene expression signature in the macrophage cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b9eee467bea600fb81c6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:202
Cell Typemacrophage
DO IDDOID:7147
Disease Nameankylosing spondylitis
Organismhuman
UMLS CUIC0038013
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM300398, GSM300399, GSM300400, GSM300401, GSM300402, GSM300403, GSM300404, GSM300405, GSM300406
Perturbed SamplesGSM300414, GSM300415, GSM300416, GSM300417, GSM300418, GSM300419, GSM300420, GSM300421
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11886
Gene Expression Omnibus
Gene expression analysis of macrophages from ankylosing spondylitis patients reveals interferon-gamma dysregulation
7
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