Small molecules which reverse colon cancer
Canned Analysis
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General Information
AccessionDCA00009743
TitleSmall molecules which reverse colon cancer
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the colon cancer gene expression signature in the Intestine - Large Intestine - Colon (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cdfee467bea600fb8bae
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:245
Cell TypeIntestine - Large Intestine - Colon (MMHCC)
DO IDDOID:219
Disease Namecolon cancer
Organismhuman
UMLS CUIC0007102
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM93938, GSM93939, GSM93941, GSM93943, GSM93944, GSM93946, GSM93948, GSM93950, GSM93952, GSM93954
Perturbed SamplesGSM93789, GSM93920, GSM93921, GSM93922, GSM93923, GSM93924, GSM93925, GSM93926, GSM93927, GSM93928, GSM93929, GSM93932
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4107
Gene Expression Omnibus
Early onset colorectal cancer: normal-appearing colonic mucosa
7
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