Small molecules which reverse Hypertrophy, Left Ventricular
Canned Analysis
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General Information
AccessionDCA00009747
TitleSmall molecules which reverse Hypertrophy, Left Ventricular
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Hypertrophy, Left Ventricular gene expression signature in the Myocardial tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cd2de467bea600fb8b46
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:248
Cell TypeMyocardial tissue
Disease NameHypertrophy, Left Ventricular
Organismrat
UMLS CUIC0149721
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM38251, GSM38252, GSM38253, GSM38254, GSM38255, GSM38256, GSM38257, GSM38258, GSM38259, GSM38260, GSM38261
Perturbed SamplesGSM38239, GSM38240, GSM38241, GSM38242, GSM38243, GSM38244, GSM38245, GSM38246, GSM38247, GSM38248, GSM38249, GSM38250
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE2116
Gene Expression Omnibus
Left ventricular hypertrophy in spontaneously hypertensive model: time course
7
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