Small molecules which mimic type 2 diabetes mellitus
Canned Analysis
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General Information
AccessionDCA00009760
TitleSmall molecules which mimic type 2 diabetes mellitus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the type 2 diabetes mellitus gene expression signature in the Renal Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cb60e467bea600fb8a64
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:25
Cell TypeRenal Tissue
DO IDDOID:9352
Disease Nametype 2 diabetes mellitus
Organismmouse
UMLS CUIC0011860
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM10401, GSM9059, GSM9069, GSM9070, GSM9071, GSM9072, GSM9073, GSM9074, GSM9075, GSM9076, GSM9169, GSM9170, GSM9171, GSM9172, GSM9173
Perturbed SamplesGSM9077, GSM9078, GSM9079, GSM9080, GSM9081, GSM9082, GSM9083, GSM9084, GSM9085, GSM9086, GSM9087, GSM9088, GSM9089, GSM9090, GSM9091, GSM9092, GSM9143, GSM9144, GSM9145, GSM9146, GSM9147, GSM9148, GSM9149, GSM9150, GSM9151, GSM9152, GSM9153, GSM9154, GSM
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE710
Gene Expression Omnibus
Diabetic nephropathy: models of type 1 and type 2 diabetes
7
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