Small molecules which mimic thrombocytopenia
Canned Analysis
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General Information
AccessionDCA00009766
TitleSmall molecules which mimic thrombocytopenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the thrombocytopenia gene expression signature in the Megakaryocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cf73e467bea600fb8c58
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:253
Cell TypeMegakaryocyte
DO IDDOID:1588
Disease Namethrombocytopenia
Organismmouse
UMLS CUIC0040034
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM48233, GSM48234, GSM48235
Perturbed SamplesGSM48230, GSM48231, GSM48232
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2527
Gene Expression Omnibus
GATA-1 knockdown effect on megakaryocytes
12
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