Small molecules which reverse primary open angle glaucoma
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00009771
TitleSmall molecules which reverse primary open angle glaucoma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the primary open angle glaucoma gene expression signature in the Optic Disk cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cec7e467bea600fb8c0e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:257
Cell TypeOptic Disk
DO IDDOID:1070
Disease Nameprimary open angle glaucoma
Organismhuman
UMLS CUIC0339573
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM52089, GSM52091
Perturbed SamplesGSM52088, GSM52090
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2705
Gene Expression Omnibus
GFAP-negative lamina cribrosa cell response to TGF-beta1
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.