Small molecules which reverse glaucoma
Canned Analysis
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General Information
AccessionDCA00009775
TitleSmall molecules which reverse glaucoma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the glaucoma gene expression signature in the Retina cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1caf9e467bea600fb8a32
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:260
Cell TypeRetina
DO IDDOID:1686
Disease Nameglaucoma
Organismmouse
UMLS CUIC0017601
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM81691, GSM81692, GSM81693
Perturbed SamplesGSM81688, GSM81689, GSM81690
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3554
Gene Expression Omnibus
DBA/2J model of glaucoma: retina
7
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