Small molecules which mimic Crohn's disease
Canned Analysis
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General Information
AccessionDCA00009784
TitleSmall molecules which mimic Crohn's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Crohn's disease gene expression signature in the sigmoid colons (mucosal biopsy) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c57fe467bea600fb8772
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:992
Cell Typesigmoid colons (mucosal biopsy)
DO IDDOID:8778
Disease NameCrohn's disease
Organismhuman
UMLS CUIC0156146
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM29595, GSM29596, GSM29597, GSM29598, GSM29599, GSM29600, GSM29601, GSM29602, GSM29603, GSM29604, GSM29605
Perturbed SamplesGSM29606, GSM29607, GSM29608, GSM29609, GSM29610, GSM29611, GSM29612, GSM29613, GSM29614, GSM29615
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1710
Gene Expression Omnibus
Crohn disease and ulcerative colitis comparison
19
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