Small molecules which mimic type 2 diabetes mellitus
Canned Analysis
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General Information
AccessionDCA00009804
TitleSmall molecules which mimic type 2 diabetes mellitus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the type 2 diabetes mellitus gene expression signature in the Muscle tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ccfae467bea600fb8b2c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:274
Cell TypeMuscle tissue
DO IDDOID:9352
Disease Nametype 2 diabetes mellitus
Organismhuman
UMLS CUIC0011860
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM317332, GSM317333, GSM317334, GSM317335, GSM317336, GSM317337, GSM317338, GSM317339, GSM317340, GSM317341
Perturbed SamplesGSM317322, GSM317323, GSM317324, GSM317325, GSM317326, GSM317327, GSM317328, GSM317329, GSM317330, GSM317331
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE12643
Gene Expression Omnibus
Type 2 diabetes: myotube
7
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