Small molecules which reverse Down syndrome
Canned Analysis
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General Information
AccessionDCA00009809
TitleSmall molecules which reverse Down syndrome
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Down syndrome gene expression signature in the Brain cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cd05e467bea600fb8b32
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:277
Cell TypeBrain
DO IDDOID:14250
Disease NameDown syndrome
Organismhuman
UMLS CUIC0013080
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM123271, GSM123272, GSM123273, GSM123274, GSM123275, GSM123276, GSM123277, GSM123278
Perturbed SamplesGSM123264, GSM123265, GSM123266, GSM123267, GSM123268, GSM123269, GSM123270
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5390
Gene Expression Omnibus
Down syndrome: brain
7
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