Small molecules which mimic alpha 1-antitrypsin deficiency
Canned Analysis
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General Information
AccessionDCA00009814
TitleSmall molecules which mimic alpha 1-antitrypsin deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the alpha 1-antitrypsin deficiency gene expression signature in the Lung Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cc20e467bea600fb8ac0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:281
Cell TypeLung Tissue
DO IDDOID:13372
Disease Namealpha 1-antitrypsin deficiency
Organismhuman
UMLS CUIC0221757
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM18403, GSM18404, GSM18405, GSM18406, GSM18407
Perturbed SamplesGSM18408, GSM18409, GSM18410, GSM18411, GSM18412
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1122
Gene Expression Omnibus
Emphysema lung tissue expression profiling
7
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