Small molecules which mimic bipolar disorder
Canned Analysis
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General Information
AccessionDCA00009844
TitleSmall molecules which mimic bipolar disorder
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the bipolar disorder gene expression signature in the frontal cortex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cbcde467bea600fb8a98
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:302
Cell Typefrontal cortex
DO IDDOID:3312
Disease Namebipolar disorder
Organismhuman
UMLS CUIC0005586
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM123253, GSM123254, GSM123255, GSM123256, GSM123257, GSM123258, GSM123259, GSM123260, GSM123261, GSM123262, GSM123263
Perturbed SamplesGSM123243, GSM123244, GSM123245, GSM123246, GSM123247, GSM123248, GSM123249, GSM123250, GSM123251, GSM123252
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5389
Gene Expression Omnibus
Bipolar disorder: orbitofrontal cortex
7
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