Small molecules which mimic Senescence
Canned Analysis
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General Information
AccessionDCA00009896
TitleSmall molecules which mimic Senescence
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Senescence gene expression signature in the CNS - Brain - Hippocampus (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c827e467bea600fb88c6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:331
Cell TypeCNS - Brain - Hippocampus (MMHCC)
Disease NameSenescence
Organismmouse
UMLS CUIC0001792
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM114426, GSM114427, GSM114428, GSM114430, GSM114431, GSM114433, GSM114434, GSM114436, GSM114437
Perturbed SamplesGSM114391, GSM114393, GSM114394, GSM114396, GSM114397, GSM114400, GSM114402, GSM114409, GSM114410, GSM114412, GSM114414, GSM114417, GSM114424, GSM114425
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5078
Gene Expression Omnibus
Age effect on the hippocampus
7
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