Small molecules which reverse Generalized seizures
Canned Analysis
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General Information
AccessionDCA00009911
TitleSmall molecules which reverse Generalized seizures
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Generalized seizures gene expression signature in the Hippocampus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b93de467bea600fb8170
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:342
Cell TypeHippocampus
Disease NameGeneralized seizures
Organismrat
UMLS CUIC0234533
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM19316, GSM19318, GSM19320, GSM19334, GSM19336, GSM19338
Perturbed SamplesGSM19344, GSM19345, GSM19346, GSM19347, GSM19348, GSM19349
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1156
Gene Expression Omnibus
Early-life kainite-induced seizure effect on brain hippocampus: time course
7
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