Small molecules which reverse allergic asthma
Canned Analysis
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General Information
AccessionDCA00009921
TitleSmall molecules which reverse allergic asthma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the allergic asthma gene expression signature in the Lung Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c267e467bea600fb85f0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:348
Cell TypeLung Tissue
DO IDDOID:9415
Disease Nameallergic asthma
Organismmouse
UMLS CUIC0155877
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM42223, GSM42224, GSM42225
Perturbed SamplesGSM42226, GSM42227, GSM42228
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2276
Gene Expression Omnibus
Asthma model of prostaglandin E receptor EP3 effect on allergic inflammation
7
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