Small molecules which reverse pre-eclampsia
Canned Analysis
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General Information
AccessionDCA00009937
TitleSmall molecules which reverse pre-eclampsia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the pre-eclampsia gene expression signature in the Placenta cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b771e467bea600fb808c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:352
Cell TypePlacenta
DO IDDOID:10591
Disease Namepre-eclampsia
Organismhuman
UMLS CUIC0032914
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM106249, GSM106250, GSM106274, GSM106275
Perturbed SamplesGSM106276, GSM106277, GSM106278, GSM106279, GSM106280, GSM106281, GSM106282, GSM106283, GSM106284, GSM106285
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4707
Gene Expression Omnibus
Early and late onset severe preeclampsia: placenta
7
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