Small molecules which mimic Schizophrenia
Canned Analysis
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General Information
AccessionDCA00009944
TitleSmall molecules which mimic Schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Schizophrenia gene expression signature in the CNS - Brain - Cerebellum (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b78de467bea600fb809a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:357
Cell TypeCNS - Brain - Cerebellum (MMHCC)
Disease NameSchizophrenia
Organismhuman
UMLS CUIC0036341
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM92460, GSM92475, GSM92476, GSM92477, GSM92478, GSM92479, GSM92480, GSM92481, GSM92482, GSM92483, GSM92484, GSM92485, GSM92486, GSM92487
Perturbed SamplesGSM92461, GSM92462, GSM92463, GSM92464, GSM92465, GSM92466, GSM92467, GSM92468, GSM92469, GSM92470, GSM92471, GSM92472, GSM92473, GSM92474
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4036
Gene Expression Omnibus
Cerebellar cortex in schizophrenia
7
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