Small molecules which reverse chronic obstructive pulmonary disease
Canned Analysis
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General Information
AccessionDCA00009951
TitleSmall molecules which reverse chronic obstructive pulmonary disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the chronic obstructive pulmonary disease gene expression signature in the Lung Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cd25e467bea600fb8b42
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:36
Cell TypeLung Tissue
DO IDDOID:3083
Disease Namechronic obstructive pulmonary disease
Organismhuman
UMLS CUIC0024117
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM28358, GSM28360, GSM28362, GSM28370, GSM28372, GSM28374, GSM28376, GSM28378, GSM28380, GSM28382, GSM28384, GSM28386
Perturbed SamplesGSM28357, GSM28359, GSM28361, GSM28363, GSM28364, GSM28365, GSM28366, GSM28367, GSM28368, GSM28369, GSM28371, GSM28373, GSM28375, GSM28377, GSM28379, GSM28381, GSM28383, GSM28385
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1650
Gene Expression Omnibus
Lung tissue from smokers with severe emphysema
7
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