Small molecules which mimic liver cirrhosis
Canned Analysis
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General Information
AccessionDCA00009962
TitleSmall molecules which mimic liver cirrhosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the liver cirrhosis gene expression signature in the Hepatic Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bc56e467bea600fb82fa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:372
Cell TypeHepatic Tissue
DO IDDOID:5082
Disease Nameliver cirrhosis
Organismrat
UMLS CUIC0023890
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM32440, GSM32441, GSM32442
Perturbed SamplesGSM32443, GSM32444, GSM32445
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1843
Gene Expression Omnibus
Cirrhosis and liver endothelial cells
7
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