Small molecules which mimic amyotrophic lateral sclerosis
Canned Analysis
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General Information
AccessionDCA00009988
TitleSmall molecules which mimic amyotrophic lateral sclerosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the amyotrophic lateral sclerosis gene expression signature in the CNS - Spinal Cord (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b887e467bea600fb8116
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:389
Cell TypeCNS - Spinal Cord (MMHCC)
DO IDDOID:332
Disease Nameamyotrophic lateral sclerosis
Organismmouse
UMLS CUIC0002736
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM99330, GSM99331
Perturbed SamplesGSM99332, GSM99334
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4390
Gene Expression Omnibus
SOD1-G93A transgenic model of amyotrophic lateral sclerosis: spinal cord
12
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