Small molecules which reverse Rett syndrome
Canned Analysis
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General Information
AccessionDCA00009993
TitleSmall molecules which reverse Rett syndrome
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Rett syndrome gene expression signature in the frontal cortex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bb77e467bea600fb828c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:390
Cell Typefrontal cortex
DO IDDOID:1206
Disease NameRett syndrome
Organismhuman
UMLS CUIC0035372
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM160306, GSM160308, GSM160310
Perturbed SamplesGSM160307, GSM160309, GSM160311
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6955
Gene Expression Omnibus
Rett syndrome: brain frontal cortex
12
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