Small molecules which reverse hypertension
Canned Analysis
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General Information
AccessionDCA00010021
TitleSmall molecules which reverse hypertension
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the hypertension gene expression signature in the Adrenal gland cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c8b9e467bea600fb8912
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:400
Cell TypeAdrenal gland
DO IDDOID:10763
Disease Namehypertension
Organismmouse
UMLS CUIC0020538
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM28678, GSM28679, GSM28680
Perturbed SamplesGSM28675, GSM28676, GSM28677
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1674
Gene Expression Omnibus
Essential hypertension BPH model
7
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