Small molecules which reverse pulmonary fibrosis
Canned Analysis
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General Information
AccessionDCA00010027
TitleSmall molecules which reverse pulmonary fibrosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the pulmonary fibrosis gene expression signature in the Lung Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c8c0e467bea600fb8916
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:406
Cell TypeLung Tissue
DO IDDOID:3770
Disease Namepulmonary fibrosis
Organismmouse
UMLS CUIC0034069
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM50717, GSM50721
Perturbed SamplesGSM50715, GSM50716, GSM50718, GSM50719, GSM50720
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2640
Gene Expression Omnibus
Bleomycin effect on lungs: dose response and time course
14
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