Small molecules which mimic Senescence
Canned Analysis
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General Information
AccessionDCA00010030
TitleSmall molecules which mimic Senescence
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Senescence gene expression signature in the frontal cortex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cb71e467bea600fb8a6c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:408
Cell Typefrontal cortex
Disease NameSenescence
Organismhuman
UMLS CUIC0001792
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM27015, GSM27016, GSM27017, GSM27018, GSM27019, GSM27020, GSM27021, GSM27022, GSM27023, GSM27024, GSM27025, GSM27026, GSM27027, GSM27028, GSM27029
Perturbed SamplesGSM27030, GSM27031, GSM27032, GSM27033, GSM27034, GSM27035, GSM27036, GSM27037, GSM27038, GSM27039, GSM27040, GSM27041, GSM27042, GSM27043, GSM27044
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1572
Gene Expression Omnibus
Aging brain: frontal cortex expression profiles at various ages
7
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