Small molecules which mimic essential hypertension
Canned Analysis
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General Information
AccessionDCA00010036
TitleSmall molecules which mimic essential hypertension
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the essential hypertension gene expression signature in the Adrenal Gland Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cd7ae467bea600fb8b6c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:412
Cell TypeAdrenal Gland Tissue
DO IDDOID:10825
Disease Nameessential hypertension
Organismrat
UMLS CUIC0085580
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM28684, GSM28685, GSM28686
Perturbed SamplesGSM28681, GSM28682, GSM28683
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1675
Gene Expression Omnibus
Essential hypertension SHR model
7
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