Small molecules which reverse cystic fibrosis
Canned Analysis
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General Information
AccessionDCA00010061
TitleSmall molecules which reverse cystic fibrosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the cystic fibrosis gene expression signature in the Pancreas cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c114e467bea600fb8558
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:428
Cell TypePancreas
DO IDDOID:1485
Disease Namecystic fibrosis
Organismmouse
UMLS CUIC0010674
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM12128, GSM6764, GSM6777
Perturbed SamplesGSM12180, GSM12181, GSM12182
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE769
Gene Expression Omnibus
Cystic fibrosis pancreatic gene expression
12
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