Small molecules which reverse Hypoxia
Canned Analysis
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General Information
AccessionDCA00010091
TitleSmall molecules which reverse Hypoxia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Hypoxia gene expression signature in the Heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c331e467bea600fb8654
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:446
Cell TypeHeart
Disease NameHypoxia
Organismmouse
UMLS CUIC0242184
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM42005, GSM42006, GSM42007, GSM42008, GSM42009, GSM42837
Perturbed SamplesGSM41995, GSM41996, GSM41997, GSM42001, GSM42002, GSM42003, GSM42004, GSM42010, GSM42011, GSM42012, GSM42013, GSM42836
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2271
Gene Expression Omnibus
Gene expression and phenotypic characterization of mouse heart after chronic constant or intermittent hypoxia
7
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