Small molecules which mimic systemic lupus erythematosus
Canned Analysis
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General Information
AccessionDCA00010100
TitleSmall molecules which mimic systemic lupus erythematosus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the systemic lupus erythematosus gene expression signature in the CD3+ T cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ccdae467bea600fb8b1c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjustinenoel
CREEDS IDdz:450
Cell TypeCD3+ T cells
DO IDDOID:9074
Disease Namesystemic lupus erythematosus
Organismhuman
UMLS CUIC0024141
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM349729, GSM349730, GSM349734, GSM349739, GSM349742, GSM349743, GSM349744, GSM349745, GSM349746
Perturbed SamplesGSM349747, GSM349748, GSM349749, GSM349764, GSM349765, GSM349766, GSM349767, GSM349768, GSM349769, GSM349770
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE13887
Gene Expression Omnibus
Systemic lupus erythematosus CD3+ T cells
14
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