Small molecules which reverse ulcerative colitis
Canned Analysis
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General Information
AccessionDCA00010125
TitleSmall molecules which reverse ulcerative colitis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the ulcerative colitis gene expression signature in the Colonic mucosa - Inflamed cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cdf7e467bea600fb8baa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:923
Cell TypeColonic mucosa - Inflamed
DO IDDOID:8577
Disease Nameulcerative colitis
Organismhuman
UMLS CUIC0375359
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM240023, GSM240024, GSM240025, GSM240026, GSM240027
Perturbed SamplesGSM239617, GSM239618, GSM239714, GSM239716, GSM239717, GSM239718, GSM239719, GSM239720
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9452
Gene Expression Omnibus
Ulcerative colitis
21
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