Small molecules which mimic cellular phase chronic idiopathic myelofibrosis
Canned Analysis
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General Information
AccessionDCA00010140
TitleSmall molecules which mimic cellular phase chronic idiopathic myelofibrosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the cellular phase chronic idiopathic myelofibrosis gene expression signature in the hematopoietic CD34+ stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c9aee467bea600fb898c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortimkenny92
CREEDS IDdz:460
Cell Typehematopoietic CD34+ stem cells
DO IDDOID:8106
Disease Namecellular phase chronic idiopathic myelofibrosis
Organismhuman
UMLS CUIC1516553
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM76923, GSM76924, GSM76925
Perturbed SamplesGSM76926, GSM76927, GSM76928
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3410
Gene Expression Omnibus
Idiopathic myelofibrosis: hematopoietic CD34+ stem cells
7
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