Small molecules which mimic breast cancer
Canned Analysis
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General Information
AccessionDCA00010192
TitleSmall molecules which mimic breast cancer
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the breast cancer gene expression signature in the MDA-MB231 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c91de467bea600fb8944
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormmluxy
CREEDS IDdz:478
Cell TypeMDA-MB231 cells
DO IDDOID:1612
Disease Namebreast cancer
Organismhuman
UMLS CUIC1458155
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM857535, GSM857536, GSM857537
Perturbed SamplesGSM857538, GSM857539, GSM857540
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34925
Gene Expression Omnibus
H3K9me2 methyltransferase G9a depletion effect on breast cancer cell line
12
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