Small molecules which mimic sickle cell anemia
Canned Analysis
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General Information
AccessionDCA00010198
TitleSmall molecules which mimic sickle cell anemia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the sickle cell anemia gene expression signature in the platelets cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cc08e467bea600fb8ab4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormmluxy
CREEDS IDdz:481
Cell Typeplatelets
DO IDDOID:10923
Disease Namesickle cell anemia
Organismhuman
UMLS CUIC0019034
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM290414, GSM290415, GSM290416, GSM290417, GSM290418, GSM290419, GSM290420, GSM290421, GSM290422, GSM290423, GSM290424, GSM290425
Perturbed SamplesGSM290396, GSM290397, GSM290398, GSM290399, GSM290400, GSM290401, GSM290402, GSM290403, GSM290404, GSM290405, GSM290406, GSM290407, GSM290408, GSM290409, GSM290410, GSM290411, GSM290412, GSM290413
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE11524
Gene Expression Omnibus
Sickle cell disease: platelets
7
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