Small molecules which reverse prostate cancer
Canned Analysis
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General Information
AccessionDCA00010205
TitleSmall molecules which reverse prostate cancer
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the prostate cancer gene expression signature in the LNCaP cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b976e467bea600fb818c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:485
Cell TypeLNCaP
DO IDDOID:10283
Disease Nameprostate cancer
Organismhuman
UMLS CUIC0376358
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM969458, GSM969460, GSM969462
Perturbed SamplesGSM969459, GSM969461, GSM969463
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39452
Gene Expression Omnibus
Expression data of EZH2-dependent genes in prostate cancer cell lines
12
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