Small molecules which reverse Cardiac Hypertrophy
Canned Analysis
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General Information
AccessionDCA00010229
TitleSmall molecules which reverse Cardiac Hypertrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Cardiac Hypertrophy gene expression signature in the Myocardial tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bdc0e467bea600fb83b0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:5
Cell TypeMyocardial tissue
Disease NameCardiac Hypertrophy
Organismmouse
UMLS CUIC1383860
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM126895, GSM126898, GSM126901, GSM126902
Perturbed SamplesGSM126903, GSM126904, GSM126905, GSM126906, GSM126907, GSM126908
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5500
Gene Expression Omnibus
Gata4 heterozygous mutant heart response to pressure overload
14
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