Small molecules which mimic Cardiac Hypertrophy
Canned Analysis
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General Information
AccessionDCA00010254
TitleSmall molecules which mimic Cardiac Hypertrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Cardiac Hypertrophy gene expression signature in the Myocardial tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cfcce467bea600fb8c80
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:51
Cell TypeMyocardial tissue
Disease NameCardiac Hypertrophy
Organismmouse
UMLS CUIC1383860
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM27631, GSM27632, GSM27633, GSM27634, GSM27639, GSM27640, GSM27641, GSM27642, GSM27648, GSM27649, GSM27650, GSM27651
Perturbed SamplesGSM27635, GSM27636, GSM27637, GSM27638, GSM27643, GSM27645, GSM27646, GSM27647, GSM27652, GSM27653, GSM27654, GSM27655, GSM27656, GSM27657
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1621
Gene Expression Omnibus
Cardiac hypertrophy progression: time course
7
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