Small molecules which mimic systemic lupus erythematosus
Canned Analysis
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General Information
AccessionDCA00010260
TitleSmall molecules which mimic systemic lupus erythematosus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the systemic lupus erythematosus gene expression signature in the synovial biopsies from affected knees cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bae1e467bea600fb8242
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvcogliani
CREEDS IDdz:512
Cell Typesynovial biopsies from affected knees
DO IDDOID:9074
Disease Namesystemic lupus erythematosus
Organismhuman
UMLS CUIC0024141
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM898470, GSM899010, GSM899011, GSM899012, GSM899013, GSM899014, GSM899015, GSM899016, GSM899017, GSM899018, GSM899019, GSM899020, GSM899025, GSM899026, GSM899027, GSM899028, GSM899029, GSM899030, GSM899031, GSM899032, GSM899033
Perturbed SamplesGSM899021, GSM899022, GSM899023, GSM899024
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36700
Gene Expression Omnibus
Systemic lupus erythematosus and arthritides: synovial biopsies
7
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