Small molecules which mimic breast cancer
Canned Analysis
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General Information
AccessionDCA00010282
TitleSmall molecules which mimic breast cancer
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the breast cancer gene expression signature in the Mammary Gland Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cfbbe467bea600fb8c78
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:52
Cell TypeMammary Gland Tissue
DO IDDOID:1612
Disease Namebreast cancer
Organismhuman
UMLS CUIC0006142
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM22369, GSM22374, GSM22381, GSM22382, GSM22384, GSM22385, GSM22387, GSM22388, GSM22390, GSM22392, GSM22393, GSM22394, GSM22397, GSM22400, GSM22401, GSM22403, GSM22404, GSM22405, GSM22406, GSM22408, GSM22409, GSM22410, GSM22413, GSM22414, GSM22417, GSM22
Perturbed SamplesGSM22365, GSM22366, GSM22367, GSM22368, GSM22370, GSM22371, GSM22372, GSM22373, GSM22375, GSM22376, GSM22377, GSM22378, GSM22379, GSM22380, GSM22383, GSM22386, GSM22389, GSM22391, GSM22395, GSM22396, GSM22398, GSM22399, GSM22402, GSM22407, GSM22411, GSM22
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1378
Gene Expression Omnibus
Estrogen positive breast cancer recurrence during tamoxifen therapy: microdissected tumor
7
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