Small molecules which mimic facioscapulohumeral muscular dystrophy
Canned Analysis
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General Information
AccessionDCA00010302
TitleSmall molecules which mimic facioscapulohumeral muscular dystrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the facioscapulohumeral muscular dystrophy gene expression signature in the skeletal muscle (biceps & deltoid) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c17be467bea600fb8586
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:540
Cell Typeskeletal muscle (biceps & deltoid)
DO IDDOID:11727
Disease Namefacioscapulohumeral muscular dystrophy
Organismhuman
UMLS CUIC0238288
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM377458, GSM377461, GSM377464, GSM377467, GSM377470
Perturbed SamplesGSM377456, GSM377459, GSM377462, GSM377465, GSM377468
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15090
Gene Expression Omnibus
Gene expression profiles in muscle tissue from FSHD patients
14
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