Small molecules which mimic schizophrenia
Canned Analysis
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General Information
AccessionDCA00010310
TitleSmall molecules which mimic schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the schizophrenia gene expression signature in the fibroblast cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c9a6e467bea600fb8988
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:547
Cell Typefibroblast
DO IDDOID:5419
Disease Nameschizophrenia
Organismhuman
UMLS CUIC0220702
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1519694, GSM1519695, GSM1519696, GSM1519697, GSM1519698
Perturbed SamplesGSM1519689, GSM1519690, GSM1519691, GSM1519692, GSM1519693
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE62105
Gene Expression Omnibus
Co-expression network analysis from genes involved with neural-differentiation shows specific pattern in patients with schizophrenia
7
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