Small molecules which mimic Premature aging
Canned Analysis
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General Information
AccessionDCA00010316
TitleSmall molecules which mimic Premature aging
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Premature aging gene expression signature in the Skin fibroblast cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cfdee467bea600fb8c88
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:55
Cell TypeSkin fibroblast
Disease NamePremature aging
Organismhuman
UMLS CUIC0231341
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM255774, GSM255806, GSM255807, GSM255808, GSM255809, GSM255828
Perturbed SamplesGSM255829, GSM255830, GSM255831, GSM255832, GSM255833, GSM255834
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10123
Gene Expression Omnibus
Progerin expression in a hTERT-immortalized skin fibroblast cell line: time course
7
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