Small molecules which reverse multiple myeloma
Canned Analysis
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General Information
AccessionDCA00010329
TitleSmall molecules which reverse multiple myeloma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the multiple myeloma gene expression signature in the Bone marrow plasma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bd38e467bea600fb836c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:561
Cell TypeBone marrow plasma cells
DO IDDOID:9538
Disease Namemultiple myeloma
Organismhuman
UMLS CUIC0026764
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1152350, GSM1152351, GSM1152352, GSM1152353, GSM1152354
Perturbed SamplesGSM1152309, GSM1152310, GSM1152311, GSM1152312, GSM1152313, GSM1152314, GSM1152315, GSM1152316, GSM1152317, GSM1152318, GSM1152319, GSM1152320, GSM1152321, GSM1152322, GSM1152323, GSM1152324, GSM1152325, GSM1152326, GSM1152327, GSM1152328, GSM1152329, GSM
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47552
Gene Expression Omnibus
Monoclonal gammopathies: bone marrow plasma cells
21
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