Small molecules which reverse asthma
Canned Analysis
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General Information
AccessionDCA00010337
TitleSmall molecules which reverse asthma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the asthma gene expression signature in the white blood cells - Male Mild Asthma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bd19e467bea600fb835c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:565
Cell Typewhite blood cells - Male Mild Asthma
DO IDDOID:2841
Disease Nameasthma
Organismhuman
UMLS CUIC0004096
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM665386, GSM665389, GSM665390, GSM665391, GSM665392, GSM665393, GSM665394, GSM665395, GSM665396, GSM665398, GSM665399, GSM665400, GSM665401, GSM665402, GSM665403
Perturbed SamplesGSM665404, GSM665405, GSM665406, GSM665407, GSM665409, GSM665413, GSM665416, GSM665417, GSM665418, GSM665419, GSM665421, GSM665422
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27011
Gene Expression Omnibus
Asthma: white blood cells
28
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