Small molecules which reverse nicotine dependence
Canned Analysis
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General Information
AccessionDCA00010371
TitleSmall molecules which reverse nicotine dependence
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the nicotine dependence gene expression signature in the lymphoblast cell lines cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c7b3e467bea600fb888c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdz:582
Cell Typelymphoblast cell lines
DO IDDOID:0050742
Disease Namenicotine dependence
Organismhuman
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM144122, GSM144123, GSM144124, GSM144125, GSM144126, GSM144127, GSM144128, GSM144129, GSM144130
Perturbed SamplesGSM144131, GSM144132, GSM144133, GSM144134, GSM144135, GSM144136
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6264
Gene Expression Omnibus
Transcriptional profiling of tobacco smokers versus controls
12
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