Small molecules which reverse ulcerative colitis
Canned Analysis
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General Information
AccessionDCA00010393
TitleSmall molecules which reverse ulcerative colitis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the ulcerative colitis gene expression signature in the colon mucosa cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bad3e467bea600fb823c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorrcaneva
CREEDS IDdz:594
Cell Typecolon mucosa
DO IDDOID:8577
Disease Nameulcerative colitis
Organismhuman
UMLS CUIC0375359
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM915451, GSM915452, GSM915453, GSM915454
Perturbed SamplesGSM915455, GSM915456, GSM915457, GSM915458, GSM915459
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE37283
Gene Expression Omnibus
Gene Expression Changes in Non-Dysplastic Mucosa from Patients with Ulcerative Colitis Harboring Remote Neoplastic Lesions
7
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