Small molecules which mimic APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Canned Analysis
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General Information
AccessionDCA00010406
TitleSmall molecules which mimic APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy gene expression signature in the Thymic epithelial cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bdc5e467bea600fb83b2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:6
Cell TypeThymic epithelial cell
Disease NameAPECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Organismmouse
UMLS CUIC0085859
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM2444, GSM2445, GSM2446
Perturbed SamplesGSM2447, GSM2448, GSM2449
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE85
Gene Expression Omnibus
Autoimmune disease mechanisms
12
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